Vladimir N Uversky Selected Research

Synucleinopathies

1/2017	Challenging drug target for Parkinson's disease: Pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins.
6/2010	Metalloproteomics and metal toxicology of α-synuclein.
1/2010	Effects of Various Flavonoids on the α-Synuclein Fibrillation Process.
10/2008	Alpha-synuclein misfolding and neurodegenerative diseases.
10/2007	Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation.
10/2003	A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders.
7/2003	Nuclear localization of alpha-synuclein and its interaction with histones.
4/2003	Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro.
7/2002	Amino acid determinants of alpha-synuclein aggregation: putting together pieces of the puzzle.
1/2002	The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein.

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Vladimir N Uversky Research Topics

Disease

61	Neoplasms (Cancer) 05/2024 - 05/2004
54	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2023 - 01/2002
46	Parkinson Disease (Parkinson's Disease) 05/2023 - 01/2002
36	COVID-19 04/2024 - 01/2020
23	Infections 12/2023 - 08/2008
22	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 07/2002
13	Amyloidosis 04/2024 - 02/2002
13	Carcinogenesis 01/2024 - 08/2006
10	Plague (Bubonic Plague) 02/2022 - 07/2002
10	Synucleinopathies 01/2017 - 01/2002
7	Breast Neoplasms (Breast Cancer) 01/2024 - 01/2007
7	Virus Diseases (Viral Diseases) 01/2023 - 03/2014
7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 06/2022 - 01/2017
6	Dementia (Dementias) 09/2014 - 07/2002
5	Melanoma (Melanoma, Malignant) 04/2024 - 05/2020
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2023 - 09/2006
5	Pathologic Processes 12/2022 - 01/2016
5	Proteostasis Deficiencies 03/2021 - 10/2006
4	Communicable Diseases (Infectious Diseases) 04/2024 - 01/2023
4	Inflammation (Inflammations) 02/2024 - 06/2007
4	Amyloid Plaque 01/2024 - 02/2002
4	Tauopathies 01/2022 - 04/2013
4	Pneumonia (Pneumonitis) 01/2022 - 11/2020
4	Multiple System Atrophy 09/2014 - 07/2002
3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 04/2024 - 06/2022
3	Post-Acute COVID-19 Syndrome 04/2024 - 12/2023
3	Neoplasm Metastasis (Metastasis) 04/2024 - 01/2023
3	Multiple Sclerosis 03/2024 - 12/2020
3	Type 2 Diabetes Mellitus (MODY) 05/2023 - 09/2017
3	Prion Diseases (Transmissible Spongiform Encephalopathies) 05/2023 - 01/2020
3	Frontotemporal Dementia (Semantic Dementia) 01/2023 - 01/2022
3	Cytokine Release Syndrome 01/2023 - 11/2021
3	Mitochondrial Diseases (Mitochondrial Disease) 02/2022 - 03/2021
3	Diabetes Mellitus 11/2021 - 10/2007
3	Cataract (Cataracts) 06/2017 - 10/2007
3	Human Influenza (Influenza) 06/2009 - 09/2008
2	Pre-Eclampsia (Preeclampsia) 04/2024 - 01/2017
2	Reinfection 04/2024 - 05/2023
2	Myocarditis (Carditis) 05/2023 - 05/2023
2	Autoimmune Diseases (Autoimmune Disease) 05/2023 - 12/2019
2	Huntington Disease (Huntington's Disease) 05/2023 - 06/2022
2	Brugada Syndrome 01/2023 - 01/2019
2	Rabies (Hydrophobia) 10/2022 - 01/2019
2	Neuroblastoma 12/2021 - 01/2019
2	Venous Thrombosis (Deep-Vein Thrombosis) 11/2021 - 08/2017
2	Thrombocytopenia (Thrombopenia) 11/2021 - 01/2021

Drug/Important Bio-Agent (IBA)

130	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2002
32	alpha-SynucleinIBA 01/2017 - 01/2002
24	Amyloid (Amyloid Fibrils)IBA 01/2024 - 02/2002
22	VaccinesIBA 04/2024 - 07/2014
20	SynucleinsIBA 11/2023 - 07/2002
19	Intrinsically Disordered ProteinsIBA 06/2022 - 10/2003
14	Peptides (Polypeptides)IBA 11/2023 - 01/2007
11	CytokinesIBA 03/2024 - 11/2016
9	Antiviral Agents (Antivirals)IBA 01/2024 - 10/2014
8	ProteomeIBA 01/2024 - 01/2012
7	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2016
6	InterferonsIBA 12/2023 - 12/2015
6	AntigensIBA 05/2023 - 07/2002
5	Messenger RNA (mRNA)IBA 12/2023 - 01/2007
5	Transcription Factors (Transcription Factor)IBA 11/2023 - 04/2017
5	EnzymesIBA 01/2023 - 01/2017
5	Protein Isoforms (Isoforms)IBA 11/2016 - 06/2013
4	mRNA VaccinesIBA 04/2024 - 05/2023
4	PrionsIBA 04/2024 - 09/2015
4	COVID-19 VaccinesIBA 12/2023 - 01/2021
4	AntibodiesIBA 12/2023 - 03/2021
4	DNA (Deoxyribonucleic Acid)IBA 08/2023 - 01/2016
4	Anti-Bacterial Agents (Antibiotics)IBA 02/2023 - 01/2016
4	Amyloid beta-PeptidesIBA 12/2021 - 12/2005
4	LactoferrinIBA 01/2021 - 01/2014
4	Carrier Proteins (Binding Protein)IBA 09/2020 - 01/2017
4	Inosine Diphosphate (IDP)IBA 01/2016 - 01/2009
4	MetalsIBA 11/2011 - 07/2003
4	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 09/2008 - 04/2002
3	Nucleocapsid ProteinsIBA 02/2024 - 09/2022
3	Immunoglobulin G (IgG)IBA 12/2023 - 01/2023
3	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2017
3	FlavonoidsIBA 05/2023 - 10/2008
3	Membrane Proteins (Integral Membrane Proteins)IBA 09/2022 - 01/2021
3	Viral ProteinsIBA 09/2022 - 02/2015
3	IronIBA 02/2022 - 10/2007
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022 - 01/2017
3	baicaleinIBA 12/2021 - 10/2008
3	LigandsIBA 09/2021 - 06/2019
3	CalreticulinIBA 05/2018 - 01/2017
3	Oleic Acid (Oleate)IBA 01/2018 - 05/2004
3	Lactalbumin (alpha-Lactalbumin)IBA 01/2018 - 05/2004
3	ChromatinIBA 01/2016 - 05/2004
2	1-methylpseudouridineIBA 05/2024 - 04/2024
2	Muramidase (Lysozyme)IBA 04/2024 - 12/2021
2	TubulinIBA 11/2023 - 01/2017
2	ErbB Receptors (EGF Receptor)IBA 11/2023 - 12/2018
2	SDMIBA 09/2022 - 01/2022
2	Toll-Like Receptors (Toll-Like Receptor)IBA 07/2022 - 03/2014
2	AndrogensIBA 11/2021 - 01/2017
2	Viral RNAIBA 09/2021 - 01/2021
2	Human Serum Albumin FDA LinkGeneric 05/2021 - 06/2019

Therapy/Procedure

27	Therapeutics 04/2024 - 10/2008
2	Drug Therapy (Chemotherapy) 04/2024 - 01/2023